Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate
Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate
CAS: 1142192-21-9
Molecular Formula: C14H17ClN2O3
Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate - Names and Identifiers
Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate - Physico-chemical Properties
| Molecular Formula | C14H17ClN2O3 |
| Molar Mass | 296.75 |
| Density | 1.245±0.06 g/cm3(Predicted) |
| Boling Point | 467.8±45.0 °C(Predicted) |
| pKa | 12.75±0.70(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11857739 |
Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate - Risk and Safety
| Hazard Class | IRRITANT |
Methyl 3-(6-chloro-5-pivalamidopyridin-2-yl)-acrylate - Introduction
Methyl 3-(+)-acrylate is an organic compound whose chemical formula is C14H17ClN2O2. Some of its properties, uses, methods and safety information are described below:
Nature:
-Appearance: colorless liquid
-Molecular weight: 288.75g/mol
-Melting Point: No Data
-Boiling Point: No Data
-Density: about 1.19 g/cm ^ 3
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use: The main use of
Methyl 3-()-acrylate is as an intermediate in the synthesis of drugs, pesticides and polymer compounds. It can be used to synthesize biologically active compounds in the pharmaceutical field, and is often used to develop anti-cancer drugs. In agriculture, it can be used as a precursor for pesticides and herbicides. In addition, it can also be used to prepare important compounds such as polymers, coatings and preservatives.
Preparation Method:
Methyl 3-(-)-acrylate synthesis method is more complex, generally requires a multi-step reaction. One of the synthetic methods is the condensation reaction of 6-chloro-5-pivalamide pyridine and methyl acrylate, followed by stereoselective reduction to obtain Methyl 3-(phenyl)-acrylate.
Safety Information:
Regarding the safety of Methyl 3-()-acrylate, the following points need to be noted:
-This compound may cause irritation and damage to health when in contact with skin, eyes or inhalation. Follow proper personal protective measures and avoid inhaling vapors or contact with skin and eyes.
-Avoid contact with oxidants and strong acids during operation to prevent flammable or explosive reactions.
-Store away from fire and high temperature, and keep the container sealed.
-If the substance is accidentally ingested or inhaled, consult a doctor promptly and provide the information needed by your doctor.
It should be noted that the information provided above is for reference only. If the compound is used in laboratory or industrial applications, the official safety data sheet and correct operating procedures should be followed.
Nature:
-Appearance: colorless liquid
-Molecular weight: 288.75g/mol
-Melting Point: No Data
-Boiling Point: No Data
-Density: about 1.19 g/cm ^ 3
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide
Use: The main use of
Methyl 3-()-acrylate is as an intermediate in the synthesis of drugs, pesticides and polymer compounds. It can be used to synthesize biologically active compounds in the pharmaceutical field, and is often used to develop anti-cancer drugs. In agriculture, it can be used as a precursor for pesticides and herbicides. In addition, it can also be used to prepare important compounds such as polymers, coatings and preservatives.
Preparation Method:
Methyl 3-(-)-acrylate synthesis method is more complex, generally requires a multi-step reaction. One of the synthetic methods is the condensation reaction of 6-chloro-5-pivalamide pyridine and methyl acrylate, followed by stereoselective reduction to obtain Methyl 3-(phenyl)-acrylate.
Safety Information:
Regarding the safety of Methyl 3-()-acrylate, the following points need to be noted:
-This compound may cause irritation and damage to health when in contact with skin, eyes or inhalation. Follow proper personal protective measures and avoid inhaling vapors or contact with skin and eyes.
-Avoid contact with oxidants and strong acids during operation to prevent flammable or explosive reactions.
-Store away from fire and high temperature, and keep the container sealed.
-If the substance is accidentally ingested or inhaled, consult a doctor promptly and provide the information needed by your doctor.
It should be noted that the information provided above is for reference only. If the compound is used in laboratory or industrial applications, the official safety data sheet and correct operating procedures should be followed.
Last Update：2024-04-09 20:52:54
